Hyper-Activation of mPFC Underlies Specific Traumatic Stress-Induced Sleep-Wake EEG Disturbances.
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SUBMITTER: Lou T
PROVIDER: S-EPMC7461881 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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Hyper-Activation of mPFC Underlies Specific Traumatic Stress-Induced Sleep-Wake EEG Disturbances.
Lou Tingting T Ma Jing J Wang Zhiqiang Z Terakoshi Yuka Y Lee Chia-Ying CY Asher Greg G Cao Liqin L Chen Zhiyu Z Sakurai Katsuyasu K Liu Qinghua Q
Frontiers in neuroscience 20200818
Sleep disturbances have been recognized as a core symptom of post-traumatic stress disorders (PTSD). However, the neural basis of PTSD-related sleep disturbances remains unclear. It has been challenging to establish the causality link between a specific brain region and traumatic stress-induced sleep abnormalities. Here, we found that single prolonged stress (SPS) could induce acute changes in sleep/wake duration as well as short- and long-term electroencephalogram (EEG) alterations in the isoge ...[more]
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