Ontology highlight
ABSTRACT:
SUBMITTER: Dundr P
PROVIDER: S-EPMC7463257 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Dundr Pavel P Bártů Michaela M Hojný Jan J Michálková Romana R Hájková Nikola N Stružinská Ivana I Krkavcová Eva E Hadravský Ladislav L Kleissnerová Lenka L Kopejsková Jana J Hiep Bui Quang BQ Němejcová Kristýna K Jakša Radek R Čapoun Otakar O Řezáč Jakub J Jirsová Kateřina K Franková Věra V
Scientific reports 20200901 1
Hepatocyte nuclear factor 1 beta (HNF1B) is a tissue specific transcription factor, which seems to play an important role in the carcinogenesis of several tumors. In our study we focused on analyzing HNF1B in prostate carcinoma (PC) and adenomyomatous hyperplasia (AH), as well as its possible relation to the upstream gene EZH2 and downstream gene ECI2. The results of our study showed that on an immunohistochemical level, the expression of HNF1B was low in PC, did not differ between PC and AH, an ...[more]