Ontology highlight
ABSTRACT:
SUBMITTER: Kleinfinger P
PROVIDER: S-EPMC7464024 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Kleinfinger Pascale P Lohmann Laurence L Luscan Armelle A Trost Detlef D Bidat Laurent L Debarge Véronique V Castaigne Vanina V Senat Marie-Victoire MV Brechard Marie-Pierre MP Guilbaud Lucie L Le Guyader Gwenaël G Satre Véronique V Laurichesse Delmas Hélène H Lallaoui Hakima H Manca-Pellissier Marie-Christine MC Boughalem Aicha A Valduga Mylene M Hodeib Farah F Benachi Alexandra A Costa Jean Marc JM
Journal of clinical medicine 20200801 8
Atypical fetal chromosomal anomalies are more frequent than previously recognized and can affect fetal development. We propose a screening strategy for a genome-wide non-invasive prenatal test (NIPT) to detect these atypical chromosomal anomalies (ACAs). Two sample cohorts were tested. Assay performances were determined using Cohort A, which consisted of 192 biobanked plasma samples-42 with ACAs, and 150 without. The rate of additional invasive diagnostic procedures was determined using Cohort B ...[more]