Ontology highlight
ABSTRACT:
SUBMITTER: Borella F
PROVIDER: S-EPMC7464214 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Borella Fulvio F Bertero Luca L Morrone Antonio A Gambella Alessandro A Bovetti Marialuisa M Cosma Stefano S Carosso Andrea A Katsaros Dionyssios D Gemmiti Silvia S Preti Mario M Valabrega Giorgio G Scotto Giulia G Cassoni Paola P Benedetto Chiara C
Cancers 20200804 8
With this review, we provide the state of the art concerning brain metastases (BMs) from ovarian cancer (OC), a rare condition. Clinical, pathological, and molecular features, treatment options, and future perspectives are comprehensively discussed. Overall, a diagnosis of high-grade serous OC and an advanced disease stage are common features among patients who develop brain metastases. <i>BRCA1</i> and <i>BRCA2</i> gene mutations, as well as the expression of androgen receptors in the primary t ...[more]