Ontology highlight
ABSTRACT:
SUBMITTER: Pecinova A
PROVIDER: S-EPMC7464303 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Pecinová Alena A Alán Lukáš L Brázdová Andrea A Vrbacký Marek M Pecina Petr P Drahota Zdeněk Z Houštěk Josef J Mráček Tomáš T
Cells 20200723 8
Prostate cancer is one of the most prominent cancers diagnosed in males. Contrasting with other cancer types, glucose utilization is not increased in prostate carcinoma cells as they employ different metabolic adaptations involving mitochondria as a source of energy and intermediates required for rapid cell growth. In this regard, prostate cancer cells were associated with higher activity of mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), the key rate limiting component of the glycerop ...[more]