Ontology highlight
ABSTRACT:
SUBMITTER: Kosnopfel C
PROVIDER: S-EPMC7464723 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Kosnopfel Corinna C Sinnberg Tobias T Sauer Birgit B Niessner Heike H Muenchow Alina A Fehrenbacher Birgit B Schaller Martin M Mertens Peter R PR Garbe Claus C Thakur Basant Kumar BK Schittek Birgit B
Cancers 20200818 8
Secreted factors play an important role in intercellular communication. Therefore, they are not only indispensable for the regulation of various physiological processes but can also decisively advance the development and progression of tumours. In the context of inflammatory disease, Y-box binding protein 1 (YB-1) is actively secreted and the extracellular protein promotes cell proliferation and migration. In malignant melanoma, intracellular YB-1 expression increases during melanoma progression ...[more]