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Epidemic Alphaviruses: Ecology, Emergence and Outbreaks.


ABSTRACT: Over the past century, the emergence/reemergence of arthropod-borne zoonotic agents has been a growing public health concern. In particular, agents from the genus Alphavirus pose a significant risk to both animal and human health. Human alphaviral disease presents with either arthritogenic or encephalitic manifestations and is associated with significant morbidity and/or mortality. Unfortunately, there are presently no vaccines or antiviral measures approved for human use. The present review examines the ecology, epidemiology, disease, past outbreaks, and potential to cause contemporary outbreaks for several alphavirus pathogens.

SUBMITTER: Azar SR 

PROVIDER: S-EPMC7464724 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Epidemic Alphaviruses: Ecology, Emergence and Outbreaks.

Azar Sasha R SR   Campos Rafael K RK   Bergren Nicholas A NA   Camargos Vidyleison N VN   Rossi Shannan L SL  

Microorganisms 20200801 8


Over the past century, the emergence/reemergence of arthropod-borne zoonotic agents has been a growing public health concern. In particular, agents from the genus <i>Alphavirus</i> pose a significant risk to both animal and human health. Human alphaviral disease presents with either arthritogenic or encephalitic manifestations and is associated with significant morbidity and/or mortality. Unfortunately, there are presently no vaccines or antiviral measures approved for human use. The present rev  ...[more]

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