Ontology highlight
ABSTRACT:
SUBMITTER: Singh CK
PROVIDER: S-EPMC7465013 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Singh Chandra K CK Chhabra Gagan G Ndiaye Mary A MA Siddiqui Imtiaz A IA Panackal Jennifer E JE Mintie Charlotte A CA Ahmad Nihal N
Cancers 20200802 8
Prostate Cancer (PCa) is a leading cause of cancer-related morbidity and mortality in men. Therefore, novel mechanistically-driven approaches are needed for PCa management. Here, we determined the effects of grape antioxidants quercetin and/or resveratrol (60 and 600 mg/kg, respectively, in diet) against PCa in Transgenic Adenocarcinoma of Mouse Prostate (TRAMP)-model in prevention and intervention settings. We found resveratrol alone and in combination significantly inhibited prostate tumorigen ...[more]