Ontology highlight
ABSTRACT:
SUBMITTER: Dumas PY
PROVIDER: S-EPMC7465142 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Dumas Pierre-Yves PY Bertoli Sarah S Bérard Emilie E Largeaud Laetitia L Bidet Audrey A Delabesse Eric E Leguay Thibaut T Leroy Harmony H Gadaud Noémie N Rieu Jean Baptiste JB Vial Jean-Philippe JP Vergez François F Lechevalier Nicolas N Luquet Isabelle I Klein Emilie E Sarry Audrey A de Grande Anne-Charlotte AC Pigneux Arnaud A Récher Christian C
Cancers 20200724 8
Two recent phase 3 trials showed that outcomes for relapsed/refractory (R/R) <i>FLT3</i>-mutated acute myeloid leukemia (AML) patients may be improved by a single-agent tyrosine kinase inhibitor (TKI) (i.e., quizartinib or gilteritinib). In the current study, we retrospectively investigated the characteristics and real-world outcomes of R/R <i>FLT3</i>-internal tandem duplication (ITD) acute myeloid leukemia (AML) patients in the Toulouse-Bordeaux DATAML registry. In the study, we included 316 p ...[more]