A Versatile and Ultrasensitive Electrochemical Sensing Platform for Detection of Chlorpromazine Based on Nitrogen-Doped Carbon Dots/Cuprous Oxide Composite.

ABSTRACT: The excessive intake of chlorpromazine (CPZ) adversely affects human health profoundly, leading to a series of severe diseases such as hepatomegaly and dyskinesia. The rapid and precise detection of CPZ in real samples is of great significance for its effective surveillance. Herein, a versatile and sensitive electrochemical sensor was developed for the detection of antipsychotic drug CPZ based on a Nafion (Nf)-supported nitrogen-doped carbon dots/cuprous oxide (N-CDs/Cu2O) composite. The as-synthesized N-CDs/Cu2O composite was systematically characterized using various physicochemical techniques. The developed composite-based sensor displayed excellent performance towards CPZ determination in a dynamic linear range of 0.001-230 µM with the detection limit of 25 nM. Remarkably, the develope

SUBMITTER: Palakollu VN 

PROVIDER: S-EPMC7466556 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature