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Risk factors for symptoms of infection and microbial carriage among French medical students abroad.


ABSTRACT:

Objectives

To investigate symptoms of infections and their risk factors among French medical students undertaking an internship abroad.

Methods

Clinical follow up, and qPCR-based respiratory, gastrointestinal, and vaginal pathogen carriages were prospectively assessed pre-travel and post-travel, in a cohort of medical students departing from Marseille, France.

Results

293 students were included. 63.5%, 35.8%, and 3.6% of students reported gastrointestinal, respiratory, and vaginal symptoms, respectively. The acquisition rate of Enteroaggregative Escherichia coli and Enteropathogenic E. coli was 40.9% and 18.6%, respectively. A significant increase was observed for rhinovirus and Streptococcus pneumoniae by comparing the prevalence of pathogens in pre-travel and post-travel samples. Gardnerella vaginalis and Atopobium vaginae acquisition rates were 12.9% and 13.9%, respectively. Being female, primarily traveling to Vietnam, and living in basic accommodation conditions were independent risk factors for reporting respiratory symptoms. Students reporting respiratory symptoms were three times more likely to acquire S. pneumoniae. Traveling primarily to north India and Senegal were independent risk factors for diarrhea.

Conclusion

This study makes it possible to identify the leading infectious diseases linked to travel in a group of French medical students undertaking an internship abroad and the risk factors on which to base targeting students for reinforced pre-travel advice.

SUBMITTER: Dao TL 

PROVIDER: S-EPMC7467057 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Publications

Risk factors for symptoms of infection and microbial carriage among French medical students abroad.

Dao Thi Loi TL   Canard Naomie N   Hoang Van Thuan VT   Ly Tran Duc Anh TDA   Drali Tassadit T   Ninove Laetitia L   Fenollar Florence F   Raoult Didier D   Parola Philippe P   Marty Pierre P   Gautret Philippe P  

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20200902


<h4>Objectives</h4>To investigate symptoms of infections and their risk factors among French medical students undertaking an internship abroad.<h4>Methods</h4>Clinical follow up, and qPCR-based respiratory, gastrointestinal, and vaginal pathogen carriages were prospectively assessed pre-travel and post-travel, in a cohort of medical students departing from Marseille, France.<h4>Results</h4>293 students were included. 63.5%, 35.8%, and 3.6% of students reported gastrointestinal, respiratory, and  ...[more]

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