Ontology highlight
ABSTRACT:
SUBMITTER: Wang C
PROVIDER: S-EPMC7467382 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Wang Chao C Shi Min M Ji Jun J Cai Qu Q Zhao Qianfu Q Jiang Jinling J Liu Jing J Zhang Huan H Zhu Zhenggang Z Zhang Jun J
Aging 20200729 15
Cancer cells are characterized by metabolic alterations. Thereinto, Stearoyl-CoA Desaturase 1 (SCD1), an enzymatic node located in the conversion of saturated fatty acids into monounsaturated fatty acids (MUFAs), has been reported to accelerate the tumorigenesis of multiple cancers. However, its role in the metabolic process of gastric cancer remains largely unexplored. In this study, by <i>in vitro</i>, <i>in vivo</i> and <i>in silico</i> assessments, our results revealed that SCD1 exhibited th ...[more]