Ontology highlight
ABSTRACT:
SUBMITTER: Ricci M
PROVIDER: S-EPMC7468673 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Ricci Maurizio M Compagna Rita R Amato Bruno B Kenanoglu Sercan S Veselenyiova Dominika D Kurti Danjela D Baglivo Mirko M Basha Syed Hussain SH Serrani Roberta R Miggiano Giacinto Abele Donato GAD Aquilanti Barbara B Matera Giuseppina G Marceddu Giuseppe G Velluti Valeria V Gagliardi Lucilla L Dundar Munis M Krajcovic Juraj J Bertelli Matteo M Bertelli Matteo M
International journal of genomics 20200825
<h4>Background</h4>ARAP3 is a small GTPase-activating protein regulator, which has important functions in lymphatic vessel organogenesis and modulation of cell adhesion and migration. Mutations in the <i>ARAP3</i> gene are associated with impaired lymphatic vessel formation.<h4>Objective</h4>The aim of our study was to determine the genotypes of lymphedema patients in relation to variants in the <i>ARAP3</i> gene in order to explore its role in the development of lymphedema.<h4>Methods and resul ...[more]