Insulin Resistance Is Associated with Reduced Food Odor Sensitivity across a Wide Range of Body Weights.

ABSTRACT: The worldwide obesity epidemic is a major health problem driven by the modern food environment. Recently, it has been shown that smell perception plays a key role in eating behavior and is altered in obesity. However, the underlying mechanisms of this phenomenon are not well understood yet. Since the olfactory system is closely linked to the endocrine system, we hypothesized that hormonal shifts in obesity might explain this relationship. In a within-subject, repeated-measures design, we investigated sensitivity to a food and a non-food odor in the hungry and sated state in 75 young healthy (26 normal weight, 25 overweight, and 24 obese) participants (37 women). To determine metabolic health status and hormonal reactivity in response to food intake, we assessed pre- and postprandial levels

SUBMITTER: Poessel M 

PROVIDER: S-EPMC7468861 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature