Ontology highlight
ABSTRACT:
SUBMITTER: Shen L
PROVIDER: S-EPMC7470023 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Shen Li L Cai Kaimin K Yu Jin J Cheng Jianjun J
Bioconjugate chemistry 20190816 9
In comparison with the popular Ac<sub>4</sub>ManNAz applied as cell labels via Cu-free click chemistry, two novel azido mannosamine lipids with C6 and C12 esters on anomeric hydroxyl groups were prepared and encapsulated in a liposome delivery system, which enhanced chemical stabilities and showed good cell-metabolizable labeling efficiency on MDA-MB-231 cells with strong fluorescence after the treatment of DBCO-Cy5 by triazole formation via click chemistry. ...[more]