Ontology highlight
ABSTRACT:
SUBMITTER: Chen F
PROVIDER: S-EPMC7471667 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Chen Fei F Zhu Li L Hu Junyan J Jiang Shujun S Liu Hui H Zheng Jie J Wang Jiandong J Wang Feng F Li Zhe Z
Oncology letters 20200828 5
Triple-negative breast cancer (TNBC) has the poorest prognosis among all types of breast cancer and there is yet no effective therapy. Chemotherapy is the traditional standard of care for patients with TNBC; however, treatment of TNBC with chemotherapy may lead to the enrichment of cancer stem cells (CSCs), which exhibitan enhanced capacity for self-renewal, tumor initiation and metastasis. The present study demonstrated that bufalin, a small molecular compound used in traditional Chinese medici ...[more]