Ontology highlight
ABSTRACT:
SUBMITTER: Panagopoulos I
PROVIDER: S-EPMC7472458 | biostudies-literature | 2020 Sep-Oct
REPOSITORIES: biostudies-literature
Panagopoulos Ioannis I Gorunova Ludmila L Andersen Kristin K Tafjord Svetlana S Lund-Iversen Marius M Lobmaier Ingvild I Micci Francesca F Heim Sverre S
Cancer genomics & proteomics 20200901 5
<h4>Background/aim</h4>Fusions of the ABL proto-oncogene 1 gene (ABL1 in 9q34) are common in leukemias but rare in solid tumors. The most notable is the t(9;22)(q34;q11)/BCR-ABL1 coding for a chimeric tyrosine kinase. We herein report an ABL1-fusion in a pediatric tumor.<h4>Materials and methods</h4>G-banding, fluorescence in situ hybridization, reverse transcription polymerase chain reaction and Sanger sequencing were performed on a soft tissue perineurioma found in the left musculus erector sp ...[more]