Macro- and microstructural changes in cosmonauts' brains after long-duration spaceflight.
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SUBMITTER: Jillings S
PROVIDER: S-EPMC7473746 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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Macro- and microstructural changes in cosmonauts' brains after long-duration spaceflight.
Jillings Steven S Van Ombergen Angelique A Tomilovskaya Elena E Rumshiskaya Alena A Litvinova Liudmila L Nosikova Inna I Pechenkova Ekaterina E Rukavishnikov Ilya I Kozlovskaya Inessa B IB Manko Olga O Danilichev Sergey S Sunaert Stefan S Parizel Paul M PM Sinitsyn Valentin V Petrovichev Victor V Laureys Steven S Zu Eulenburg Peter P Sijbers Jan J Wuyts Floris L FL Jeurissen Ben B
Science advances 20200904 36
Long-duration spaceflight causes widespread physiological changes, although its effect on brain structure remains poorly understood. In this work, we acquired diffusion magnetic resonance imaging to investigate alterations of white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) compositions in each voxel, before, shortly after, and 7 months after long-duration spaceflight. We found increased WM in the cerebellum after spaceflight, providing the first clear evidence of sensorimotor ...[more]
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