Ontology highlight
ABSTRACT:
SUBMITTER: Chaudhari J
PROVIDER: S-EPMC7474429 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Chaudhari Jayeshbhai J Liew Chia-Sin CS Workman Aspen M AM Riethoven Jean-Jack M JM Steffen David D Sillman Sarah S Vu Hiep L X HLX
Viruses 20200728 8
Both virulent and live-attenuated porcine reproductive and respiratory syndrome virus (PRRSV) strains can establish persistent infection in lymphoid tissues of pigs. To investigate the mechanisms of PRRSV persistence, we performed a transcriptional analysis of inguinal lymphoid tissue collected from pigs experimentally infected with an attenuated PRRSV strain at 46 days post infection. A total of 6404 differentially expressed genes (DEGs) were detected of which 3960 DEGs were upregulated and 244 ...[more]