A tree shrew model for steroid-associated osteonecrosis.
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ABSTRACT:
SUBMITTER: Chen Q
PROVIDER: S-EPMC7475020 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Publications
A tree shrew model for steroid-associated osteonecrosis.
Chen Qi Q Ma Zhao-Xia ZX Xia Li-Bin LB Ye Zhen-Ni ZN Liu Bao-Ling BL Ma Tie-Kun TK Bao Peng-Fei PF Wu Xing-Fei XF Yu Cong-Tao CT Ma Dai-Ping DP Han Yuan-Yuan YY Wang Wen-Guang WG Kuang De-Xuan DX Dai Jie-Jie JJ Zhang Rong-Ping RP Hu Min M Shi Hong H Wang Wen-Lin WL Li Yan-Jiao YJ
Zoological research 20200901 5
Osteonecrosis is a common human disease in orthopedics. It is difficult to treat, and half of patients may need artificial joint replacement, resulting in a considerable economic burden and a reduction in quality of life. Hormones are one of the major causes of osteonecrosis and high doses of corticosteroids are considered the most dangerous factor. Because of the complexity of treatment, we still need a better animal model that can be widely used in drug development and testing. Tree shrews are ...[more]
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