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Extensive Ethnolinguistic Diversity in Vietnam Reflects Multiple Sources of Genetic Diversity.

ABSTRACT: Vietnam features extensive ethnolinguistic diversity and occupies a key position in Mainland Southeast Asia. Yet, the genetic diversity of Vietnam remains relatively unexplored, especially with genome-wide data, because previous studies have focused mainly on the majority Kinh group. Here, we analyze newly generated genome-wide single-nucleotide polymorphism data for the Kinh and 21 additional ethnic groups in Vietnam, encompassing all five major language families in Mainland Southeast Asia. In addition to analyzing the allele and haplotype sharing within the Vietnamese groups, we incorporate published data from both nearby modern populations and ancient samples for comparison. In contrast to previous studies that suggested a largely indigenous origin for Vietnamese genetic diversity, we find that Vietnamese ethnolinguistic groups harbor multiple sources of genetic diversity that likely reflect different sources for the ancestry associated with each language family. However, linguistic diversity does not completely match genetic diversity: There have been extensive interactions between the Hmong-Mien and Tai-Kadai groups; different Austro-Asiatic groups show different affinities with other ethnolinguistic groups; and we identified a likely case of cultural diffusion in which some Austro-Asiatic groups shifted to Austronesian languages during the past 2,500?years. Overall, our results highlight the importance of genome-wide data from dense sampling of ethnolinguistic groups in providing new insights into the genetic diversity and history of an ethnolinguistically diverse region, such as Vietnam.

SUBMITTER: Liu D

PROVIDER: S-EPMC7475039 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Extensive Ethnolinguistic Diversity in Vietnam Reflects Multiple Sources of Genetic Diversity.

Liu Dang D Duong Nguyen Thuy NT Ton Nguyen Dang ND Van Phong Nguyen N Pakendorf Brigitte B Van Hai Nong N Stoneking Mark M

Molecular biology and evolution 20200901 9

Vietnam features extensive ethnolinguistic diversity and occupies a key position in Mainland Southeast Asia. Yet, the genetic diversity of Vietnam remains relatively unexplored, especially with genome-wide data, because previous studies have focused mainly on the majority Kinh group. Here, we analyze newly generated genome-wide single-nucleotide polymorphism data for the Kinh and 21 additional ethnic groups in Vietnam, encompassing all five major language families in Mainland Southeast Asia. In ...[more]

PMID: 32344428

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Dataset Information

Extensive Ethnolinguistic Diversity in Vietnam Reflects Multiple Sources of Genetic Diversity.

Publications

Extensive Ethnolinguistic Diversity in Vietnam Reflects Multiple Sources of Genetic Diversity.

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