Ontology highlight
ABSTRACT:
SUBMITTER: Chen GQ
PROVIDER: S-EPMC7475738 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Chen Guo-Qing GQ Ye Ping P Ling Rong-Song RS Zeng Fa F Zhu Xiong-Shan XS Chen Lu L Huang Yan Y Xu Ling L Xie Xiao-Ying XY
Stem cells international 20200829
Ovarian cancer is a highly deadly disease, which is often diagnosed at a late stage with metastases. However, most ovarian cancers relapse after surgery combined with platinum-based chemotherapy. Cancer stem cells (CSCs) are stem-like cells that possess high tumorigenic capability and display higher resistant capability against current therapies. However, our knowledge of ovarian CSCs and their molecular mechanism remains sparse. In the current study, we found that KDM4C, a histone demethylase, ...[more]