Ontology highlight
ABSTRACT:
SUBMITTER: Li SS
PROVIDER: S-EPMC7476117 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
American journal of translational research 20200815 8
Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a systemic autoimmune disease characterized by leukocytoclastic inflammation of small blood vessels. Commonly detected autoantibodies include anti-protease 3 (PR3) and anti-myeloperoxidase (MPO). Although cell necrosis plays an important role in the production of autoantibodies and the pathogenesis of AAV, the correlation between their titers and disease activity remains elusive. As improved detection techniques facilitat ...[more]