Ontology highlight
ABSTRACT:
SUBMITTER: Ma CG
PROVIDER: S-EPMC7476160 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Ma Chun-Guang CG Xu Wen-Hao WH Xu Yue Y Wang Jun J Liu Wang-Rui WR Cao Da-Long DL Wang Hong-Kai HK Shi Guo-Hai GH Zhu Yi-Ping YP Qu Yuan-Yuan YY Zhang Hai-Liang HL Ye Ding-Wei DW
American journal of translational research 20200815 8
Patients with clear cell renal cell carcinoma (ccRCC) typically face aggressive disease progression when metastasis occurs. Here, we screened and identified differentially expressed genes in three microarray datasets from the Gene Expression Omnibus database. We identified 112 differentially expressed genes with functional enrichment as candidate prognostic biomarkers. Lasso Cox regression suggested 10 significant oncogenic hub genes involved in earlier recurrence and poor prognosis of ccRCC. Re ...[more]