Ontology highlight
ABSTRACT:
SUBMITTER: Zhao X
PROVIDER: S-EPMC7476931 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Zhao Xiaolong X Peng Yu Y Li Xuemei X Zhang Shiheng S Peng Yang Y Shan Jinlu J Li Mengxia M Dai Nan N Feng Yan Y Xu Chengxiong C Wang Dong D
International journal of clinical and experimental pathology 20200801 8
<h4>Objective</h4>To investigate the influence of PD-L1 polymorphisms on the susceptibility of non-small-cell lung cancer (NSCLC) and the prognosis of NSCLC patients who undergo platinum-based chemotherapy.<h4>Materials and methods</h4>9 single nucleotide polymorphisms (SNPs) in the PD-L1 gene, including rs822336 (G>C), rs822337 (T>A), rs10815225 (G>C), rs7866740 (C>G), rs866066 (C>T), rs822338 (C>T), rs2890657 (C>G), rs2890658 (C>A), and rs229136 (C>G) were selected for this study. Genotyping w ...[more]