Unknown

Dataset Information

0

Association of Alopecia Areata with Vitamin D and Calcium Levels: A Systematic Review and Meta-analysis.


ABSTRACT: INTRODUCTION:To investigate the associations of alopecia areata (AA) with serum vitamin D and calcium levels. METHODS:A systematic review of all relevant articles published up to February 2020 in PubMed, Embase, and Cochrane Library databases was conducted. Primary endpoints were serum 25-hydroxyvitamin D [25(OH)D] levels and vitamin D deficiency, and the secondary endpoint was serum calcium level. Odds ratio (OR) and standardized mean difference (SMD) with 95% CI across studies were analyzed. RESULTS:Data on 1585 patients with AA and 1114 controls from 16 case-control studies and three cross-sectional studies were included in this meta-analysis. A pooled meta-analysis was conducted using the random-effects model because of inter-study heterogeneity (vitamin D level, I2?=?87.90%; vitamin D deficiency, I2?=?81.10%; serum calcium level, I2?=?83.80%). A combined analysis revealed that patients with AA had significantly lower mean serum 25(OH)D level compared with control (WMD -?9.08, 95% CI -?11.65, -?6.50, p?

SUBMITTER: Liu Y 

PROVIDER: S-EPMC7477029 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

altmetric image

Publications

Association of Alopecia Areata with Vitamin D and Calcium Levels: A Systematic Review and Meta-analysis.

Liu Yi Y   Li Jing J   Liang Guirong G   Cheng Chaojiang C   Li Yue Y   Wu Xinfeng X  

Dermatology and therapy 20200809 5


<h4>Introduction</h4>To investigate the associations of alopecia areata (AA) with serum vitamin D and calcium levels.<h4>Methods</h4>A systematic review of all relevant articles published up to February 2020 in PubMed, Embase, and Cochrane Library databases was conducted. Primary endpoints were serum 25-hydroxyvitamin D [25(OH)D] levels and vitamin D deficiency, and the secondary endpoint was serum calcium level. Odds ratio (OR) and standardized mean difference (SMD) with 95% CI across studies w  ...[more]

Similar Datasets

| S-EPMC6883433 | biostudies-literature
| S-EPMC6133534 | biostudies-literature
| S-EPMC8556406 | biostudies-literature
| S-EPMC5527723 | biostudies-other
| S-EPMC6233743 | biostudies-literature
| S-EPMC9793131 | biostudies-literature
| S-EPMC6240665 | biostudies-literature
| S-EPMC5573125 | biostudies-other
| S-EPMC8814138 | biostudies-literature
| S-EPMC4488802 | biostudies-other