Cerebrovascular risk factors impact frontoparietal network integrity and executive function in healthy ageing.
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ABSTRACT:
SUBMITTER: Veldsman M
PROVIDER: S-EPMC7477206 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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Cerebrovascular risk factors impact frontoparietal network integrity and executive function in healthy ageing.
Veldsman Michele M Tai Xin-You XY Nichols Thomas T Smith Steve S Peixoto João J Manohar Sanjay S Husain Masud M
Nature communications 20200907 1
Healthy cognitive ageing is a societal and public health priority. Cerebrovascular risk factors increase the likelihood of dementia in older people but their impact on cognitive ageing in younger, healthy brains is less clear. The UK Biobank provides cognition and brain imaging measures in the largest population cohort studied to date. Here we show that cognitive abilities of healthy individuals (N = 22,059) in this sample are detrimentally affected by cerebrovascular risk factors. Structural eq ...[more]
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