Recent advances in understanding primary ovarian insufficiency.
Ontology highlight
ABSTRACT:
SUBMITTER: Wesevich V
PROVIDER: S-EPMC7477642 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Recent advances in understanding primary ovarian insufficiency.
Wesevich Victoria V Kellen Amanada N AN Pal Lubna L
F1000Research 20200907
Primary ovarian insufficiency (POI) is an uncommon yet devastating occurrence that results from a premature depletion of the ovarian pool of primordial follicles. Our understanding of both putative and plausible mechanisms underlying POI, previously considered to be largely "idiopathic", has been furthered over the past several years, largely due to advances in the field of genetics and through expansion of translational models for experimental research. In this review, our goal is to familiariz ...[more]
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