Ontology highlight
ABSTRACT:
SUBMITTER: Recondo G
PROVIDER: S-EPMC7478969 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Recondo Gonzalo G Mahjoubi Linda L Maillard Aline A Loriot Yohann Y Bigot Ludovic L Facchinetti Francesco F Bahleda Rastislav R Gazzah Anas A Hollebecque Antoine A Mezquita Laura L Planchard David D Naltet Charles C Lavaud Pernelle P Lacroix Ludovic L Richon Catherine C Lovergne Aurelie Abou AA De Baere Thierry T Tselikas Lambros L Deas Olivier O Nicotra Claudio C Ngo-Camus Maud M Frias Rosa L RL Solary Eric E Angevin Eric E Eggermont Alexander A Olaussen Ken A KA Vassal Gilles G Michiels Stefan S Andre Fabrice F Scoazec Jean-Yves JY Massard Christophe C Soria Jean-Charles JC Besse Benjamin B Friboulet Luc L
NPJ precision oncology 20200908
Unravelling the biological processes driving tumour resistance is necessary to support the development of innovative treatment strategies. We report the design and feasibility of the MATCH-R prospective trial led by Gustave Roussy with the primary objective of characterizing the molecular mechanisms of resistance to cancer treatments. The primary clinical endpoints consist of analyzing the type and frequency of molecular alterations in resistant tumours and compare these to samples prior to trea ...[more]