Calcium Dynamics in Astrocytes During Cell Injury.
Ontology highlight
ABSTRACT:
SUBMITTER: Wakida NM
PROVIDER: S-EPMC7481337 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Calcium Dynamics in Astrocytes During Cell Injury.
Wakida Nicole M NM Gomez-Godinez Veronica V Li Huayan H Nguyen Jessica J Kim Edward K EK Dynes Joseph L JL Othy Shivashankar S Lau Alice L AL Ding Peng P Shi Linda L Carmona Christopher C Thompson Leslie M LM Cahalan Michael D MD Berns Michael W MW
Frontiers in bioengineering and biotechnology 20200827
The changes in intracellular calcium concentration ([Ca<sup>2+</sup>]) following laser-induced cell injury in nearby cells were studied in primary mouse astrocytes selectively expressing the Ca<sup>2+</sup> sensitive GFAP-Cre Salsa6f fluorescent tandem protein, in an Ast1 astrocyte cell line, and in primary mouse astrocytes loaded with Fluo4. Astrocytes in these three systems exhibit distinct changes in [Ca<sup>2+</sup>] following induced death of nearby cells. Changes in [Ca<sup>2+</sup>] appea ...[more]
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