Chronic neural activity recorded within breast tumors.
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ABSTRACT:
SUBMITTER: McCallum GA
PROVIDER: S-EPMC7481786 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Publications
Chronic neural activity recorded within breast tumors.
McCallum Grant A GA Shiralkar Jay J Suciu Diana D Covarrubias Gil G Yu Jennifer S JS Karathanasis Efstathios E Durand Dominique M DM
Scientific reports 20200909 1
Nerve fibers are known to reside within malignant tumors and the greater the neuronal density the worse prognosis for the patient. Recent discoveries using tumor bearing animal models have eluded to the autonomic nervous system having a direct effect on tumor growth and metastasis. We report the first direct and chronic in vivo measurements of neural activity within tumors. Using a triple-negative mammary cancer mouse model and chronic neural interface techniques, we have recorded neural activit ...[more]
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