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Antiviral Nanostructured Surfaces Reduce the Viability of SARS-CoV-2.

ABSTRACT: In this letter, we report the ability of the nanostructured aluminum Al 6063 alloy surfaces to inactivate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There was no recoverable viable virus after 6 h of exposure to the nanostructured surface, elucidating a 5-log reduction compared to a flat Al 6063 surface. The nanostructured surfaces were fabricated using wet-etching techniques which generated nanotextured, randomly aligned ridges approximately 23 nm wide on the Al 6063 alloy surfaces. In addition to the excellent mechanical resilience properties previously shown, the etched surfaces have also demonstrated superior corrosion resistance compared to the control surfaces. Such nanostructured surfaces have the potential to be used in healthcare environment such as hospitals and public spaces to reduce the surface transmission of SARS-CoV-2 and combat COVID-19.

SUBMITTER: Hasan J

PROVIDER: S-EPMC7482073 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Antiviral Nanostructured Surfaces Reduce the Viability of SARS-CoV-2.

Hasan Jafar J Pyke Alyssa A Nair Neelima N Yarlagadda Tejasri T Will Geoffrey G Spann Kirsten K Yarlagadda Prasad K D V PKDV

ACS biomaterials science & engineering 20200902 9

In this letter, we report the ability of the nanostructured aluminum Al 6063 alloy surfaces to inactivate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). There was no recoverable viable virus after 6 h of exposure to the nanostructured surface, elucidating a 5-log reduction compared to a flat Al 6063 surface. The nanostructured surfaces were fabricated using wet-etching techniques which generated nanotextured, randomly aligned ridges approximately 23 nm wide on the Al 6063 allo ...[more]

PMID: 33455218

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