Dataset Information

Time trends of delirium rates in the intensive care unit.

ABSTRACT:

Background

Effects of clinical practice changes on ICU delirium are not well understood.

Objectives

Determine ICU delirium rates over time.

Methods

Data from a previously described screening cohort of the Pharmacological Management of Delirium trial was analyzed. Richmond Agitation-Sedation Scale (RASS) and Confusion Assessment Method for the ICU (CAM-ICU) were assessed twice daily. We defined: Any delirium (positive CAM-ICU at any time during ICU stay) and ICU-acquired delirium (1st CAM-ICU negative with a subsequent positive CAM-ICU). Mixed-effects logistic regression models were used to test for differences.

Results

2742 patient admissions were included. Delirium occurred in 16.5%, any delirium decreased [22.7% to 10.2% (p < 0.01)], and ICU-acquired delirium decreased [8.4% to 4.4% (p = 0.01)]. Coma decreased from 24% to 17.4% (p = 0.04). Later ICU years and higher mean RASS scores were associated with lower odds of delirium.

Conclusions

Delirium rates were not explained by the measured variables and further prospective research is needed.

SUBMITTER: Khan SH

PROVIDER: S-EPMC7483280 | biostudies-literature |

REPOSITORIES: biostudies-literature

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