Ontology highlight
ABSTRACT:
SUBMITTER: Muranen TA
PROVIDER: S-EPMC7483417 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
NPJ breast cancer 20200910
Germline genetic variation has been suggested to influence the survival of breast cancer patients independently of tumor pathology. We have studied survival associations of genetic variants in two etiologically unique groups of breast cancer patients, the carriers of germline pathogenic variants in <i>BRCA1</i> or <i>BRCA2</i> genes. We found that rs57025206 was significantly associated with the overall survival, predicting higher mortality of <i>BRCA1</i> carrier patients with estrogen receptor ...[more]