The feasibility of [18F]EF5-PET/CT to image hypoxia in ovarian tumors: a clinical study.
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SUBMITTER: Laasik M
PROVIDER: S-EPMC7483702 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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The feasibility of [<sup>18</sup>F]EF5-PET/CT to image hypoxia in ovarian tumors: a clinical study.
Laasik Maren M Hynninen Johanna J Forsback Sarita S Noponen Tommi T Seppänen Marko M Hietanen Sakari S
EJNMMI research 20200910 1
<h4>Rationale</h4>Evaluation of the feasibility of [<sup>18</sup>F]EF5-PET/CT scan in identifying hypoxic lesions in ovarian tumors in prospective clinical setting.<h4>Methods</h4>Fifteen patients with a suspected malignant ovarian tumor were scanned with [<sup>18</sup>F]EF5 and [<sup>18</sup>F]FDG-PET/CT preoperatively. The distribution of [<sup>18</sup>F]EF5-uptake, total intraabdominal metabolic tumor volume (TMTV), and hypoxic subvolume (HSV) were assessed.<h4>Results</h4>[<sup>18</sup>F]EF5 ...[more]
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