Ontology highlight
ABSTRACT:
SUBMITTER: Yan Y
PROVIDER: S-EPMC7486193 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Yan Yi Y Wang Rui R Hu Xiongji X Wang Shichao S Zhang Liang L Hou Chenjiao C Zhang Lisheng L
Stem cell reports 20200806 3
Liver progenitor cells (LPCs) have a remarkable contribution to the hepatocytes and ductal cells when normal hepatocyte proliferation is severely impaired. As a biomarker for LPCs, Sry-box 9 (Sox9) plays critical roles in liver homeostasis and repair in response to injury. However, the regulation mechanism of Sox9 in liver physiological and pathological state remains unknown. In this study, we found that miR-126 positively regulated the expression of Sox9, the proliferation and differentiation o ...[more]