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The impact of COVID-19 on health status of home-dwelling elderly patients with dementia in East Lombardy, Italy: results from COVIDEM network.


ABSTRACT:

Background

COVID-19 outbreak has led to severe health burden in the elderly. Age, morbidity and dementia have been associated with adverse outcome.

Aims

To evaluate the impact of COVID-19 on health status in home-dwelling patients.

Methods

848 home-dwelling outpatients with dementia contacted from April 27 to 30 and evaluated by a semi-structured interview to evaluate possible health complication due to COVID-19 from February 21 to April 30. Age, sex, education, clinical characteristics (including diagnosis of dementia) and flu vaccination history were obtained from previous medical records. Items regarding change in health status and outcome since the onset of the outbreak were collected. COVID-19 was diagnosed in patients who developed symptoms according to WHO criteria or tested positive at nasal/throat swab if hospitalized. Unplanned hospitalization, institutionalization and mortality were recorded.

Results

Patients were 79.7 years old (SD 7.1) and 63.1% were females. Ninety-five (11.2%) patients developed COVID-19-like symptoms. Non COVID-19 and COVID-19 patients differed for frequency of diabetes (18.5% vs. 37.9%, p < 0.001), COPD (7.3% vs. 18.9%, p < 0.001), and previous flu vaccination (56.7% vs. 37.9%, p < 0.001). Diabetes and COPD were positively associated with COVID-19, whereas higher dementia severity and flu vaccination showed an inverse association. Among COVID-19 patients, 42 (44.2%) were hospitalized while 32 (33.7%) died. Non COVID-19 patients' hospitalization and mortality rate were 1.9% and 1.2%, respectively. COVID-19 and COPD were significantly associated with the rate of mortality.

Discussion/conclusions

A high proportion of adverse outcome related to COVID-19 was observed in home-dwelling elderly patients with dementia. Active monitoring though telehealth programs would be useful particularly for those at highest risk of developing COVID-19 and its adverse outcomes.

SUBMITTER: Caratozzolo S 

PROVIDER: S-EPMC7486591 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Publications

The impact of COVID-19 on health status of home-dwelling elderly patients with dementia in East Lombardy, Italy: results from COVIDEM network.

Caratozzolo Salvatore S   Zucchelli Alberto A   Turla Marinella M   Cotelli Maria Sofia MS   Fascendini Sara S   Zanni Mara M   Bianchetti Angelo A   Psy Matteo Peli MP   Rozzini Renzo R   Boffelli Stefano S   Cappuccio Melania M   Psy Federica Gottardi FG   Psy Chiara Vecchi CV   Bellandi Daniele D   Caminati Claudia C   Gentile Simona S   Psy Elena Lucchi EL   Di Fazio Ignazio I   Psy Marina Zanetti MZ   Vezzadini Giuliana G   Psy Chiara Forlani CF   Psy Maura Cosseddu MC   Psy Rosanna Turrone RT   Psy Silvia Pelizzari SP   Scalvini Andrea A   Di Cesare Marco M   Psy Marta Grigolo MG   Falanga Lina L   Medici Nives N   Palamini Nives N   Psy Elisa Zanacchi EZ   Psy Eleonora Grossi EG   Bellelli Giuseppe G   Marengoni Alessandra A   Trabucchi Marco M   Padovani Alessandro A  

Aging clinical and experimental research 20200912 10


<h4>Background</h4>COVID-19 outbreak has led to severe health burden in the elderly. Age, morbidity and dementia have been associated with adverse outcome.<h4>Aims</h4>To evaluate the impact of COVID-19 on health status in home-dwelling patients.<h4>Methods</h4>848 home-dwelling outpatients with dementia contacted from April 27 to 30 and evaluated by a semi-structured interview to evaluate possible health complication due to COVID-19 from February 21 to April 30. Age, sex, education, clinical ch  ...[more]

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