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Phenolic content, chemical composition and anti-/pro-oxidant activity of Gold Milenium and Papierowka apple peel extracts.

ABSTRACT: In this study the peels of ecologically grown apple (Malus domestica) cultivars: Gold Milenium (a new scab-resistant variety) and Papierowka (Papirovka; an old, sensitive to apple scab variety) were examined for their composition (phenolic compounds, triterpenoids, simple organic acids, macro-, microelements, reducing sugars, L-ascorbic acid), pro- and antioxidant properties as well as their application in reduction of the oxidative stress in cultured human skin fibroblast. The higher content of phenolic compounds correlated with the greater pro- and antioxidant activity of the peels of Papierowka compared to Gold Milenium in DPPH·, ABTS⁺, FRAP and CUPRAC assays as well as an ability to inhibition of lipid peroxidation. The quantity of the compounds strongly depended on the type of extraction. The extract of Papierowka peels possessed much higher amount of phenolic compounds compared to Gold Milenium (Papierowka: 3.68?±?0.20 mg/g peel ultrasound assisted extraction (u.a.e); 2.02?±?0.13 mg/g peel conventional extraction (c.e.); Gold Milenium: 1.46?±?0.19 mg/g peel u.a.e; 1.15?±?0.04 mg/g peel c.e. according the HPLC measurement). The pro-oxidant activity of the extract from Papierowka peels can be correlated with the content of phenolic compounds and metal ions as well. The apple peel extract is promising agent reducing the oxidative stress in skin fibroblast.

SUBMITTER: Kalinowska M

PROVIDER: S-EPMC7486935 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Phenolic content, chemical composition and anti-/pro-oxidant activity of Gold Milenium and Papierowka apple peel extracts.

Kalinowska Monika M Gryko Kamila K Wróblewska Anna M AM Jabłońska-Trypuć Agata A Karpowicz Danuta D

Scientific reports 20200911 1

In this study the peels of ecologically grown apple (Malus domestica) cultivars: Gold Milenium (a new scab-resistant variety) and Papierowka (Papirovka; an old, sensitive to apple scab variety) were examined for their composition (phenolic compounds, triterpenoids, simple organic acids, macro-, microelements, reducing sugars, L-ascorbic acid), pro- and antioxidant properties as well as their application in reduction of the oxidative stress in cultured human skin fibroblast. The higher content of ...[more]

PMID: 32917912

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Project description:Currently, oxidative stress is one of the major problems that threatens human health. It is at the root of many diseases such as cancer. Despite the enormous efforts provided to combat this scourge, oxidative stress is still relevant and hence comes the need for research of new remedies especially from natural origin. For this purpose, the study of the antioxidant activity of extracts of Cistus monspeliensis from Morocco is a principal research objective. The phenolic extracts were obtained by maceration of the plant in a water/acetone mixture and then separated by liquid/liquid extraction with solvents of increasing polarity. The first phytochemical tests carried out on these extracts showed the existence of different families of phenolic compounds, such as flavonoids, tannins, and others. Assays for total polyphenols, flavonoids, hydrolysable, and condensed tannins were carried out by known colorimetric methods. The results of these assays have shown that the studied extracts are rich in phenolic compounds present in the plant in the form of flavonoids (69.81 ± 0.22 mg EQ/g DM), hydrolysable tannins (61.86 ± 0.89 mg ETA/g DM), and condensed tannins (70.05 ± 1.61 mg EC/g DM). The evaluation of the antioxidant activity is carried out by two different methods: the DPPH test (2,2-DiPhenyl-1-Picryl-Hydrazyl) and the FRAP test (Ferric Reducing Antioxidant Power). The results obtained show that the extracts of Cistus monspeliensis are active and have interesting antioxidant powers. In particular, the water/acetone (WAE) (IC50 = 0.079 mg/mL) and butanolic (BUE) (IC0.5 = 0.099 mg/mL) extracts are the most active with values comparable to that of ascorbic acid. The interesting results obtained in this study clearly show that Cistus monspeliensis originating from Morocco can be considered as a source of natural antioxidants. Therefore, the extracts of this plant deserve to be tested in the medicinal field, against cancer and cardiovascular diseases, and in food field as an additive and preservative.

Dataset Information

Phenolic content, chemical composition and anti-/pro-oxidant activity of Gold Milenium and Papierowka apple peel extracts.

Publications

Phenolic content, chemical composition and anti-/pro-oxidant activity of Gold Milenium and Papierowka apple peel extracts.

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