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Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis.


ABSTRACT: Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction-based diagnosis, the microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower.

SUBMITTER: Churiso G 

PROVIDER: S-EPMC7486950 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Minimally Invasive Microbiopsies as an Improved Sampling Method for the Diagnosis of Cutaneous Leishmaniasis.

Churiso Gemechu G   van Henten Saskia S   Cnops Lieselotte L   Pollmann Julia J   Melkamu Roma R   Lemma Mulualem M   Kiflie Amare A   Fikre Helina H   van Griensven Johan J   Adriaensen Wim W  

Open forum infectious diseases 20200817 9


Current sampling methods to diagnose cutaneous leishmaniasis are invasive and painful. An alternative and minimally invasive microbiopsy device was evaluated in a diverse range of cutaneous leishmaniasis lesions in Ethiopia. Using polymerase chain reaction-based diagnosis, the microbiopsy outperformed the routine skin slit sample by detecting more patients while pain scores were significantly lower. ...[more]

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