Ontology highlight
ABSTRACT:
SUBMITTER: Chia YC
PROVIDER: S-EPMC7487096 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Chia Yvonne Cashinn YC Anjum Clarice Evey CE Yee Hui Rong HR Kenisi Yenny Y Chan Mike K S MKS Wong Michelle B F MBF Pan Shing Yi SY
Stem cells international 20200904
Blood-brain barrier (BBB) is a term describing the highly selective barrier formed by the endothelial cells (ECs) of the central nervous system (CNS) homeostasis by restricting movement across the BBB. An intact BBB is critical for normal brain functions as it maintains brain homeostasis, modulates immune cell transport, and provides protection against pathogens and other foreign substances. However, it also prevents drugs from entering the CNS to treat neurodegenerative diseases. Stem cells, on ...[more]