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CATSLife: A Study of Lifespan Behavioral Development and Cognitive Functioning.


ABSTRACT: The purpose of this update is to provide the most current information about both the Colorado Adoption Project (CAP) and the Longitudinal Twin Study (LTS) and to introduce the Colorado Adoption/Twin Study of Lifespan behavioral development and cognitive aging (CATSLife), a product of their merger and a unique study of lifespan behavioral development and cognitive aging. The primary objective of CATSLife is to assess the unique saliency of early childhood genetic and environmental factors to adult cognitive maintenance and change, as well as proximal influences and innovations that emerge across development. CATSLife is currently assessing up to 1600 individuals on the cusp of middle age, targeting those between 30 and 40 years of age. The ongoing CATSLife data collection is described as well as the longitudinal data available from the earlier CAP and LTS assessments. We illustrate CATSLife via current projects and publications, highlighting the measurement of genetic, biochemical, social, sociodemographic and environmental indices, including geospatial features, and their impact on cognitive maintenance in middle adulthood. CATSLife provides an unparalleled opportunity to assess prospectively the etiologies of cognitive change and test the saliency of early childhood versus proximal influences on the genesis of cognitive decline.

SUBMITTER: Wadsworth SJ 

PROVIDER: S-EPMC7487141 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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CATSLife: A Study of Lifespan Behavioral Development and Cognitive Functioning.

Wadsworth Sally J SJ   Corley Robin P RP   Munoz Elizabeth E   Trubenstein B Paige BP   Knaap Elijah E   DeFries John C JC   Plomin Robert R   Reynolds Chandra A CA  

Twin research and human genetics : the official journal of the International Society for Twin Studies 20190924 6


The purpose of this update is to provide the most current information about both the Colorado Adoption Project (CAP) and the Longitudinal Twin Study (LTS) and to introduce the Colorado Adoption/Twin Study of Lifespan behavioral development and cognitive aging (CATSLife), a product of their merger and a unique study of lifespan behavioral development and cognitive aging. The primary objective of CATSLife is to assess the unique saliency of early childhood genetic and environmental factors to adul  ...[more]

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