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Perioperative risk factors predict one-year mortality in patients with acute type-A aortic dissection.


ABSTRACT:

Objective

The goal of this study was to analyze perioperative risk factors to predict one- year mortality after operation for acute type A aortic dissection (AAD).

Methods

A total of 121 consecutive patients undergoing Stanford type A AAD surgery in Beijing Anzhen Hospital were enrolled. Preoperative clinical and laboratory data from patients were collected.

Results

Multivariable Cox regression analysis showed that significant factors associated with increased one-year mortality were elder age (year) (hazard ratio (HR) 1.0985; 95% confidence interval (CI) 1.0334-1.1677), intraoperative blood transfusion ≥2000 mL (HR 8.8081; 95% CI 2.3319-33.2709), a higher level of serum creatinine (μmol/L) at postoperative one day (HR 1.0122; 95% CI 1.0035-1.0190) and oxygenation index (OI) < 200 (mmHg) at the end of surgery (HR 5.7575; 95% CI 1.1695-28.3458).

Conclusion

In this study, perioperative risk factors to predict one-year prognosis are age, intraoperative blood transfusion ≥2000 mL, postoperative OI < 200 mmHg and level of postoperative serum creatinine. The results aid in the comprehension of surgical outcomes and assist in the optimization of treatment strategies for those with perioperative risk factors to decrease one-year mortality.

SUBMITTER: Yang Y 

PROVIDER: S-EPMC7488853 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Publications

Perioperative risk factors predict one-year mortality in patients with acute type-A aortic dissection.

Yang Yanwei Y   Xue Jiayi J   Li Huixian H   Tong Jiaqi J   Jin Mu M  

Journal of cardiothoracic surgery 20200911 1


<h4>Objective</h4>The goal of this study was to analyze perioperative risk factors to predict one- year mortality after operation for acute type A aortic dissection (AAD).<h4>Methods</h4>A total of 121 consecutive patients undergoing Stanford type A AAD surgery in Beijing Anzhen Hospital were enrolled. Preoperative clinical and laboratory data from patients were collected.<h4>Results</h4>Multivariable Cox regression analysis showed that significant factors associated with increased one-year mort  ...[more]

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