Medical, Genomic, and Evolutionary Aspects of the Peptide Sharing between Pathogens, Primates, and Humans.
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ABSTRACT:
SUBMITTER: Kanduc D
PROVIDER: S-EPMC7490124 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Publications
Medical, Genomic, and Evolutionary Aspects of the Peptide Sharing between Pathogens, Primates, and Humans.
Kanduc Darja D Shoenfeld Yehuda Y
Global medical genetics 20200831 2
Comparing mammalian proteomes for molecular mimicry with infectious pathogens highlights the highest levels of heptapeptide sharing between pathogens and human, murine, and rat proteomes, while the peptide sharing level is minimal (or absent) with proteomes from nonhuman primates such as gorilla, chimpanzee, and rhesus macaque. From the medical point of view, the data might be useful to clinicians and vaccinologists to develop and evaluate immunomodulatory and immunotherapeutic approaches. As a ...[more]
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