Ontology highlight
ABSTRACT:
SUBMITTER: Panoutsopoulos AA
PROVIDER: S-EPMC7490522 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Panoutsopoulos Alexios A AA De Crescenzo Angelo Harlan AH Lee Albert A Lu Amelia MacKenzie AM Ross Adam P AP Borodinsky Laura N LN Marcucio Ralph R Trainor Paul A PA Zarbalis Konstantinos S KS
Frontiers in cell and developmental biology 20200901
Neural crest cells (NCCs) comprise a transient progenitor cell population of neuroepithelial origin that contributes to a variety of cell types throughout vertebrate embryos including most mesenchymal cells of the cranial and facial structures. Consequently, abnormal NCC development underlies a variety of craniofacial defects including orofacial clefts, which constitute some of the most common birth defects. We previously reported the generation of <i>manta ray</i> (<i>mray</i>) mice that carry ...[more]