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Discrete-Event Simulation Modeling of Critical Care Flow: New Hospital, Old Challenges.

ABSTRACT: Objectives:As the demand for critical care beds rises each year, hospitals must be able to adapt. Delayed transfer of care reduces available critical care capacity and increases occupancy. The use of mathematic modeling within healthcare systems has the ability to aid planning of resources. Discrete-event simulation models can determine the optimal number of critical care beds required and simulate different what-if scenarios. Design:Complex discrete-event simulation model was developed using a warm-up period of 30 days and ran for 30 trials against a 2-year period with the mean calculated for the runs. A variety of different scenarios were investigated to determine the effects of increasing capacity, increasing demand, and reduction of proportion and length of delayed transfer of care out of the ICU. Setting:Combined data from two ICUs in United Kingdom. Patients:The model was developed using 1,728 patient records and was validated against an independent dataset of 2,650 patients. Interventions:None. Measurements and Main Results:During model validation, the average bed utilization and admittance rate were equal to the real-world data. In the what-if scenarios, we found that increasing bed numbers from 23 to 28 keeping the arrival rate stable reduces the average occupancy rate to 70%. We found that the projected 4% yearly increase in admissions could overwhelm even the 28-bedded unit, without change in the delayed transfer of care episodes. Reduction in the proportion of patients experiencing delayed transfer of care had the biggest effect on occupancy rates, time spent at full capacity, and average bed utilization. Conclusions:Using discrete-event simulation of commonly available baseline patient flow and patient care data produces reproducible models. Reducing the proportion of patients with delayed transfer of care had a greater effect in reducing occupancy levels than simply increasing bed numbers even when demand is increased.

SUBMITTER: Williams E

PROVIDER: S-EPMC7491890 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Discrete-Event Simulation Modeling of Critical Care Flow: New Hospital, Old Challenges.

Williams Elizabeth E Szakmany Tamas T Spernaes Izabela I Muthuswamy Babu B Holborn Penny P

Critical care explorations 20200914 9

<h4>Objectives</h4>As the demand for critical care beds rises each year, hospitals must be able to adapt. Delayed transfer of care reduces available critical care capacity and increases occupancy. The use of mathematic modeling within healthcare systems has the ability to aid planning of resources. Discrete-event simulation models can determine the optimal number of critical care beds required and simulate different what-if scenarios.<h4>Design</h4>Complex discrete-event simulation model was dev ...[more]

PMID: 32984824

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Project description:ObjectiveHealthcare faces the continual challenge of improving outcome while aiming to reduce cost. The aim of this study was to determine the micro cost differences of the Glasgow non-operative trauma virtual pathway in comparison to a traditional pathway.DesignDiscrete event simulation was used to model and analyse cost and resource utilisation with an activity-based costing approach. Data for a full comparison before the process change was unavailable so we used a modelling approach, comparing a virtual fracture clinic (VFC) with a simulated traditional fracture clinic (TFC).SettingThe orthopaedic unit VFC pathway pioneered at Glasgow Royal Infirmary has attracted significant attention and interest and is the focus of this cost study.Outcome measuresOur study focused exclusively on patients with non-operative trauma attending emergency department or the minor injuries unit and the subsequent step in the patient pathway. Retrospective studies of patient outcomes as a result of the protocol introductions for specific injuries are presented in association with activity costs from the models.ResultsPatients are satisfied with the new pathway, the information provided and the outcome of their injuries (Evidence Level IV). There was a 65% reduction in the number of first outpatient face-to-face (f2f) attendances in orthopaedics. In the VFC pathway, the resources required per day were significantly lower for all staff groups (p≤0.001). The overall cost per patient of the VFC pathway was £22.84 (95% CI 21.74 to 23.92) per patient compared with £36.81 (95% CI 35.65 to 37.97) for the TFC pathway.ConclusionsOur results give a clearer picture of the cost comparison of the virtual pathway over a wholly traditional f2f clinic system. The use of simulation-based stochastic costings in healthcare economic analysis has been limited to date, but this study provides evidence for adoption of this method as a basis for its application in other healthcare settings.

Project description:ObjectivesThis feasibility study aimed to model in silico the current healthcare system for patients triaged to a primary care disposition following a call to National Health Service (NHS) 111 and determine the effect of reconfiguring the healthcare system to ensure a timely primary care service contact.DesignDiscrete event simulation.SettingSingle English NHS 111 call centre in Yorkshire.ParticipantsCallers registered with a Bradford general practitioner who contacted the NHS 111 service in 2021 and were triaged to a primary care disposition.Primary and secondary outcome measuresFace validity of conceptual model. Comparison between real and simulated data for quarterly counts (and 95% CIs) for patient contact with emergency ambulance (999), 111, and primary and secondary care services. Mean difference and 95% CIs in healthcare system usage between simulations and difference in mean proportion of avoidable admissions for callers who presented to an emergency department (ED).ResultsThe simulation of the current system estimated that there would be 39 283 (95% CI 39 237 to 39 328) primary care contacts, 2042 (95% CI 2032 to 2051) 999 calls and 1120 (95% CI 1114 to 1127) avoidable ED attendances. Modifying the model to ensure a timely primary care response resulted in a mean percentage increase of 196.1% (95% CI 192.2% to 199.9%) in primary care contacts, and a mean percentage decrease of 78.0% (95% CI 69.8% to 86.2%) in 999 calls and 88.1% (95% CI 81.7% to 94.5%) in ED attendances. Avoidable ED attendances reduced by a mean of -26 (95% CI -35 to -17).ConclusionIn this simulated study, ensuring timely contact with a primary care service would lead to a significant reduction in 999 and 111 calls, and ED attendances (although not avoidable ED attendance). However, this is likely to be impractical given the need to almost double current primary care service provision. Further economic and qualitative research is needed to determine whether this intervention would be cost-effective and acceptable to both patients and primary care clinicians.

Project description:BACKGROUND:Different strategies toward implementing competing risks in discrete-event simulation (DES) models are available. This study aims to provide recommendations regarding modeling approaches that can be defined based on these strategies by performing a quantitative comparison of alternative modeling approaches. METHODS:Four modeling approaches were defined: 1) event-specific distribution (ESD), 2) event-specific probability and distribution (ESPD), 3) unimodal joint distribution and regression model (UDR), and 4) multimodal joint distribution and regression model (MDR). Each modeling approach was applied to uncensored individual patient data in a simulation study and a case study in colorectal cancer. Their performance was assessed in terms of relative event incidence difference, relative absolute event incidence difference, and relative entropy of time-to-event distributions. Differences in health economic outcomes were also illustrated for the case study. RESULTS:In the simulation study, the ESPD and MDR approaches outperformed the ESD and UDR approaches, in terms of both event incidence differences and relative entropy. Disease pathway and data characteristics, such as the number of competing risks and overlap between competing time-to-event distributions, substantially affected the approaches' performance. Although no considerable differences in health economic outcomes were observed, the case study showed that the ESPD approach was most sensitive to low event rates, which negatively affected performance. CONCLUSIONS:Based on overall performance, the recommended modeling approach for implementing competing risks in DES models is the MDR approach, which is defined according to the general strategy of selecting the time-to-event first and the corresponding event second. The ESPD approach is a less complex and equally performing alternative if sufficient observations are available for each competing event (i.e., the internal validity shows appropriate data representation).

Dataset Information

Discrete-Event Simulation Modeling of Critical Care Flow: New Hospital, Old Challenges.

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Discrete-Event Simulation Modeling of Critical Care Flow: New Hospital, Old Challenges.

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