The association between triglycerides and incident cardiovascular disease: What is "optimal"?

ABSTRACT:

Background

Elevated triglycerides (TGs) are associated with increased risk of cardiovascular disease (CVD), but the best way to both measure TGs and assess TG-related risk remains unknown.

Objective

The objective of the study was to evaluate the association between TGs and CVD and determine whether the average of a series of TG measurements is more predictive of CVD risk than a single TG measurement.

Methods

We examined 15,792 study participants, aged 40-65 years, free of CVD from the Atherosclerosis Risk in Communities and Framingham Offspring studies, using fasting TG measurements across multiple examinations over time. With up to 10 years of follow-up, we assessed time-to-first CVD event, as well as a composite of myocardial infarction, stroke, or cardiovascular de

SUBMITTER: Aberra T 

PROVIDER: S-EPMC7492406 | biostudies-literature | 2020 Jul - Aug

REPOSITORIES: biostudies-literature