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Low-cost and versatile electrodes for extracellular chronic recordings in rodents.

ABSTRACT: Electrophysiological data are used to investigate fundamental properties of brain function, its relation to cognition, and its dysfunction in diseases. The development of reliable and open-source systems for electrophysiological data acquisition is decreasing the total cost of constructing and operating an electrophysiology laboratory, and facilitates low-cost methods to extract and analyze the data (Siegle et al., 2017). Here we detail our method of building custom-designed low-cost electrodes. These electrodes can be customized and manufactured by any researcher to address a broad set of research questions, further decreasing the final cost of an implanted animal. Finally, we present data showing such an electrode has a good signal quality to record LFP.

SUBMITTER: Franca ASC 

PROVIDER: S-EPMC7492997 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Low-cost and versatile electrodes for extracellular chronic recordings in rodents.

França Arthur S C ASC   van Hulten Josephus A JA   Cohen Michael X MX  

Heliyon 20200914 9

Electrophysiological data are used to investigate fundamental properties of brain function, its relation to cognition, and its dysfunction in diseases. The development of reliable and open-source systems for electrophysiological data acquisition is decreasing the total cost of constructing and operating an electrophysiology laboratory, and facilitates low-cost methods to extract and analyze the data (Siegle et al., 2017). Here we detail our method of building custom-designed low-cost electrodes.  ...[more]