Dataset Information

Further resolution of the house mouse (Mus musculus) phylogeny by integration over isolation-with-migration histories.

ABSTRACT:

Background

The three main subspecies of house mice, Mus musculus castaneus, Mus musculus domesticus, and Mus musculus musculus, are estimated to have diverged ~?350-500KYA. Resolution of the details of their evolutionary history is complicated by their relatively recent divergence, ongoing gene flow among the subspecies, and complex demographic histories. Previous studies have been limited to some extent by the number of loci surveyed and/or by the scope of the method used. Here, we apply a method (IMa3) that provides an estimate of a population phylogeny while allowing for complex histories of gene exchange.

Results

Results strongly support a topology with M. m. domesticus as sister to M. m. castaneus and M. m. musculus. In addition, we find evidence of gene flow between all pairs of subspecies, but that gene flow is most restricted from M. m. musculus into M. m. domesticus. Estimates of other key parameters are dependent on assumptions regarding generation time and mutation rate in house mice. Nevertheless, our results support previous findings that the effective population size, N_e, of M. m. castaneus is larger than that of the other two subspecies, that the three subspecies began diverging ~?130 - 420KYA, and that the time between divergence events was short.

Conclusions

Joint demographic and phylogenetic analyses of genomic data provide a clearer picture of the history of divergence in house mice.

SUBMITTER: Phifer-Rixey M

PROVIDER: S-EPMC7493149 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Publications

Further resolution of the house mouse (Mus musculus) phylogeny by integration over isolation-with-migration histories.

Phifer-Rixey Megan M Harr Bettina B Hey Jody J

BMC evolutionary biology 20200915 1

<h4>Background</h4>The three main subspecies of house mice, Mus musculus castaneus, Mus musculus domesticus, and Mus musculus musculus, are estimated to have diverged ~ 350-500KYA. Resolution of the details of their evolutionary history is complicated by their relatively recent divergence, ongoing gene flow among the subspecies, and complex demographic histories. Previous studies have been limited to some extent by the number of loci surveyed and/or by the scope of the method used. Here, we appl ...[more]

PMID: 32933487

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Project description:Abstract: Background:Communal nursing in house mice is an example of cooperation where females pool litters in the same nest and indiscriminately nurse own and other offspring despite potential exploitation. The direct fitness benefits associated with communal nursing shown in laboratory studies suggest it to be a selected component of female house mice reproductive behaviour. However, past studies on communal nursing in free-living populations have debated whether it is a consequence of sharing the same nest or an active choice. Here using data from a long-term study of free-living, wild house mice we investigated individual nursing decisions and determined what factors influenced a female's decision to nurse communally. Results:Females chose to nurse solitarily more often than expected by chance, but the likelihood of nursing solitarily decreased when females had more partners available. While finding no influence of pairwise relatedness on partner choice, we observed that females shared their social environment with genetically similar individuals, suggesting a female's home area consisted of related females, possibly facilitating the evolution of cooperation. Within such a home area females were more likely to nest communally when the general relatedness of her available options was relatively high. Females formed communal nests with females that were familiar through previous associations and had young pups of usually less than 5 days old. Conclusions:Our findings suggest that communal nursing was not a by-product of sharing the same nesting sites, but females choose communal nursing partners from a group of genetically similar females, and ultimately the decision may then depend on the pool of options available. Social partner choice proved to be an integrated part of cooperation among females, and might allow females to reduce the conflict over number of offspring in a communal nest and milk investment towards own and other offspring. We suggest that social partner choice may be a general mechanism to stabilize costly cooperation.

Dataset Information

Further resolution of the house mouse (Mus musculus) phylogeny by integration over isolation-with-migration histories.

Background

Results

Conclusions

Publications

Further resolution of the house mouse (Mus musculus) phylogeny by integration over isolation-with-migration histories.

Similar Datasets

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