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Clinical characteristics and quality of life in seborrheic dermatitis patients: a cross-sectional study in China.

ABSTRACT: BACKGROUND:Seborrheic dermatitis (SD) is a common, chronic, inflammatory skin disorder, yet few studies have reported its clinical characteristics, or addressed its effect on quality of life (QoL). This study assesses the clinical characteristics and QoL of SD patients in China. It also identifies the clinical, demographic and environmental factors that may influence QoL. METHODS:Three hundred twelve SD outpatients from 9 hospitals completed a survey. QoL was measured with the dermatology-specific instrument Skindex-29. We collected social demographic characteristics and disease severity, and conducted logistic regression to determine the factors associated with QoL impairment. RESULTS:67.3% of the patients were females. The mean Skindex-29 overall score was 33.97 (SD?=?20.55). The breakdown was 40.79 (SD?=?24.24) for emotions, 32.83 (SD?=?19.84) for symptoms and 28.3 (SD?=?23.24) for functioning. 48.1% had severe emotional problems. Logistic regression analysis showed that BMI less than 25 (OR?=?0.223; 95% CI: 0.072-0.692; P?=?0.009), skin disease-related hospitalization (OR?=?6.882; 95% CI:1.767-26.795; P?=?0.005), environmental PM 10 levels above 120??g/m3 (OR?=?3.386; 95% CI: 1.253-9.15; P?=?0.016) and severe disease conditions (OR?=?4.438; 95% CI:1.26-15.626; P?=?0.02) were risk factors for severe emotional impairment. Moreover, skin disease-related hospitalization (OR?=?6.057; 95% CI:1.351-27.149; P?=?0.019), environmental PM 10 levels between 70 and 120??g/m3 (OR?=?6.317; 94% CI: 1.704-23.42; P?=?0.006), moderate (OR?=?2.388; 95% CI: 1.272-4.487; P?=?0.007) and severe disease conditions (OR?=?5.732; 95% CI: 1.838-17.88; P?=?0.003) were each risk factors for overall severe impairment. CONCLUSION:In China, nearly half of SD patients had severely emotional problems. Disease severity, BMI, dermatologic hospitalization, and ambient PM 10 levels are each risk factors for QoL impairment in SD patients. These implications are alarming, and warrant public health attention in SD disease management.

SUBMITTER: Xuan M

PROVIDER: S-EPMC7493366 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Clinical characteristics and quality of life in seborrheic dermatitis patients: a cross-sectional study in China.

Xuan Meiling M Lu Chuanjian C He Zehui Z

Health and quality of life outcomes 20200916 1

<h4>Background</h4>Seborrheic dermatitis (SD) is a common, chronic, inflammatory skin disorder, yet few studies have reported its clinical characteristics, or addressed its effect on quality of life (QoL). This study assesses the clinical characteristics and QoL of SD patients in China. It also identifies the clinical, demographic and environmental factors that may influence QoL.<h4>Methods</h4>Three hundred twelve SD outpatients from 9 hospitals completed a survey. QoL was measured with the der ...[more]

PMID: 32938485

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Project description:To assess the quality of life (QoL) of caregivers of children with sickle cell disease (SCD) and to determine the risk factors associated with poor QoL.A cross sectional study was conducted between 01 and 30 June 2015, in a tertiary care center in western Saudi Arabia to assess various dimensions of QoL by using TNO-AZL Questionnaire for Adult's Health-related Quality of Life (TAAQOL). A total 164 adult caregivers (aged 16 years or more) of children with SCD, who were regularly visiting the department were enrolled (refusal rate?=?61.6%). The questionnaire scores were transformed into 0-100 scale; with higher scores indicating less difficulty and better QoL Demographic, socioeconomic data and a satisfaction questionnaire regarding participants' lifestyle were collected and analyzed as risk factors for impaired QoL, by comparing different QoL dimensions' scores using independent t-test, Oneway ANOVA, or linear regression, as appropriate.Sixty-three caregivers were included; 79.4% were mothers, age range 21-71 years, 64.5% were from low social class receiving insufficient support and financial needs were unmet for considerable number of families. Analysis of QoL using TAAQOL showed that emotions (median [75th centile]?=?44.44 [66.67] for negative and 61.11 [72.22] for positive emotions), sleep quality (66.67 [91.67]) and sexual life (50.00 [83.33]) were the most affected dimensions. Professional achievement (91.67 [100]), cognitive skills (83.33 [100]), and social contact (100 [100]) were relatively preserved. Negative emotions were more marked in mothers and mostly predicted by satisfaction with social relations notably with partner (B?=?3.14, p?=?0.016), friends (B?=?2.51, p?=?0.015) and relatives (B?=?2.69, p?=?0.016). Positive emotions were predicted by the levels of satisfaction of the caregiver with his/her health (B?=?2.56, p?=?0.001), job achievement (B?=?4.54, p?=?0.001), living conditions (B?=?2.60, p?=?0.034) and the condition of the diseased child (B?=?2.55, p?=?0.011). A strong correlation was found between sleep quality and cognitive skills.There are notable financial and emotional burdens on the caregivers of children with SCD affecting various aspects of their QoL, which are likely to be impacted by the individual levels of social and professional achievement. Physicians and health authorities should give particular attention to the QoL of caregivers and families of children with SCD, to help them cope up with the disease and overcome its related psychological and financial impacts.

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Dataset Information

Clinical characteristics and quality of life in seborrheic dermatitis patients: a cross-sectional study in China.

Publications

Clinical characteristics and quality of life in seborrheic dermatitis patients: a cross-sectional study in China.

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