Decreased neural inhibitory state in fibromyalgia pain: A cross-sectional study.

ABSTRACT:

Objectives

Chronic pain is one of the most common and challenging symptoms in fibromyalgia (FM). Currently, self-reported pain is the main criterion used by clinicians assessing patients with pain. However, it is subjective, and multiple factors can affect pain levels. In this study, we investigated the neural correlates of FM pain using conditioned pain modulation (CPM), electroencephalography (EEG), and transcranial magnetic stimulation (TMS).

Methods

In this cross-sectional neurophysiological analysis of a randomized, double-blind controlled trial, 36 patients with fibromyalgia were included. We analyzed CPM, EEG variables and TMS measures and their correlation with pain levels as measured by a visual analog scale. Univariate and multivariate linear regression analyses we

SUBMITTER: Uygur-Kucukseymen E 

PROVIDER: S-EPMC7494538 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature